Fibromyalgia Syndrome Research articles from March

Some of the most interesting research relevant to Fibromyalgia Syndrome (Fibro) that has been discussed in the FibroAction Research section the last month is summarised here.

Low levels of antioxidant vitamins in plasma of patients with Fibromyalgia Syndrome

A recently published study has found that the concentrations of vitamins A and E in the blood plasma of patients with Fibromyalgia Syndrome are significantly lower than in healthy controls.

The aim of the study was to investigate the levels of antioxidant vitamins in the blood of patients with Fibro compared to healthy people, as well as the levels of lipid peroxidation (how much fatty acids in the body have been damaged by free radicals, which antioxidant vitamins work against), and the levels of nitric oxide.

The researchers found that concentrations of vitamins A and E were significantly lower in patients with Fibro, and lipid peroxidation levels were significantly higher, suggesting a role for the fat-soluble antioxidant vitamins A & E in Fibro. Concentrations of vitamin C and beta-carotene and levels of NO were not significantly different in the Fibro patients.

Sleep Apnoea can cause Fibromyalgia Syndrome type symptoms in partners

A recent study by researchers in Brazil has shown that the wives of men with sleep apnoea are at risk of developing disturbed sleep and other symptoms of Fibromyalgia Syndrome.

Decreased corneal sensitivity and tear production in Fibromyalgia Syndrome

A recent study by researchers in Spain has shown that people with Fibromyalgia Syndrome suffer from dry eyes and that their corneas do not respond as well to a number of stimuli, including chemicals, heat and cold.

Intravenous lidocaine for Fibromyalgia Syndrome

A recent study has found that intravenous lidocaine infusions are safe and effective in the management of Fibro.

Twenty-three Fibro patients took part in the study, and received 5 intravenous infusions, one a day for 5 days. The dosages of lidocaine given in the infusion were increased over the 5 day period. Significant improvements were seen after the fifth infusion, with the benefits lasting for ast leat 20 days.

Review of Guidelines for the management of Fibromyalgia Syndrome

An article has been e-published reviewing the available evidence based guidelines for the management of Fibro.

Three evidence-based guidelines for the management of Fibro published by professional organisations were identified: The American Pain Society (2005), the European League Against Rheumatism (EULAR), and the AWMF (2008). The researchers found that although they differed slightly, all three recommended a multi-disciplinary treatment, involving both medications and non-medications therapies, such as hydrotherapy, exercise and cognitive behavioural therapy (CBT).