Autonomic Dysfunction in Fibromyalgia Syndrome

Dysfunction of the autonomic nervous system is common in Fibromyalgia Syndrome (Fibro) and may play a part in a number of symptoms, according to a recent article by American Fibro expert Roland Staud MD. [1]

The autonomic nervous system regulates many important biological functions, such as heart rate, blood pressure, respirations, and bowel function.

Dr Staud notes in the article that, although Fibro is defined by chronic widespread pain and tenderness, additional symptoms, including disabling fatigue and dizziness, are often reported by patients. [1]

Whilst nonrestorative sleep may play an important role in the chronic fatigue of Fibro, dysfunction of the autonomic nervous system should be considered as a possible cause of fatigue. [1]

Dysfunction of the autonomic nervous system can be a condition in its own right - Dysautonomia - and it is usually characterised by either Neurocardiogenic Syncope (fainting) and/or Postural Orthostatic Tachycardia (heart beat racing when moving from lying down to sitting or sitting to standing). Palpitations and dizziness are part of this condition and are also possible symptoms of Fibro.

Head-up tilt table testing can be used to evaluate autonomic dysfunction and Dr Staud states that this is frequently helpful when investigating possible symptoms of Fibro, including fatigue, dizziness, and palpitations. [1]

Dr Staud notes that one of the most common events experienced by Fibro patients during tilt table testing is Postural Orthostatic Tachycardia Syndrome (POTS), which is defined as a heart rate increase of more than 30 beats per minute after more than 3 minutes of standing upright. [1]

For more information on Dysautonomia, try the Dysautonomia Information Network

References:

1. Staud R. Autonomic dysfunction in fibromyalgia syndrome: postural orthostatic tachycardia. Curr Rheumatol Rep. 2008 Dec;10(6):463-6.